Revul - Stops the bleeding

Revul saving lives!

Revul Stops the bleeding

Learn how
Revul HEMOSTATIC DRESSING
Revul HEMOSTATIC POWDER

Revul Mechanism of action

Revul HEMOSTATIC DRESSING

Hemostatic effect is regardless of blood coagulation processes in the body and caused by binding of positively charged elements of dressing material with negatively charged erythrocytes. When contacting with blood, hemostatic dressing Revul (Ревул) enhances the absorption of blood liquid fraction and forms a single gel-tremellose mass, thus facilitating the hemostasis.

Revul HEMOSTATIC POWDER

When the powder interacting with blood, Revul forms hydrogen compounds with water (as blood consist 90-95% of water), which leads to the aggregation formed elements of blood and clotting factors at the site of contact followed by the formation of a blood clot. This occurs due to the large molecular weight of molecules, which are full of the hydroxyl groups.

Revul Clinical effects

Revul HEMOSTATIC DRESSING
  • The average time of a dense clot formation varies between 25 and 30 seconds.
  • A nonwoven material based on the pure chitosan, but not impregnated synthetic material, is used.
  • Chitosan meets international standards FDA GRAS (Generally Recognized as safe).
  • It does not mix with blood and does not get into the lumen of blood vessels.
  • Chitosan shows the effect regardless of blood clotting processes in the body.
  • It has a large useful area of contact with the surface of a wound for rapid bleeding control.
  • Optimal area of the gauze for use in large and medium-sized wounds that are the most difficult for the patient.
  • Concentration of chitosan for rapid haemostasis is not less than 100 grams which increases the speed of haemostatic effect.
  • It meets NATO standards applying to haemostatic gauze for military personnel and is suitable for use in peacetime.
Revul HEMOSTATIC POWDER
  • Effectively stops the bleeding of different intensity in 5-10 min.
  • Does not affects blood clotting factors, is effective in the conditions of anticoagulation.
  • Does not affects hemostasis directly.
  • Creates a clot in the presence of heparin and indirect anticoagulants.
  • Revul does not adhere and does not stick to the damaged tissues. When the doctor removes the clot, Revul easily washes away with the saline. Then treat the wound according to the approved medical standards.
  • Revul does not cause a thermal reaction at the site of application and does not cause burns.
  • Probability of allergic reactions is very low, as in human body no enzymes that can split the main components of REVUL.

Revul Dosing and Administration

1

Take the REVUL® hemostatic dressing pouch, check the package integrity, open the pouch and take out the dressing.

2

Perform a tight tamponade of the wound, preferably, above the source of bleeding. Leave hemostatic dressing in the wound. Rests of the dressing can be cut off or pick off if necessary. DO NOT DISCARD THE EMPTY PACKAGE!

3

Press tightly a gauze tampon to the wound for 5 minutes. Apply a compressing bandage to the wound.

4

Seek medical attention at the nearest first aid station as soon as possible.

5

Give the empty pouch to medical professionals.

6

Do not use the remainders of the roll gauze.

1

Wound in the start of bleeding.

2

To provide maximum contact of powder with the damaged vessel clean the wound from the foreign bodies, blood clots.

3

Fill the wound with package content. DO NOT DISCARD THE EMPTY PACKAGE!

4
5-7 minutes

Press firmly to the wound with a bandage or gauze pack for 5-7 minutes.

5

Stable wound.

6

Apply a pressure bandage on the wound.

Do not throw an empty package!
It may be needed by medical personnel to identify a haemostatic agent.

As soon as possible, take the patient to the nearest first aid. Pass an empty packet to medical professionals. Do not use any powder residue.

Reviews about Revul

Military medic
Combat experience in the south and east of Ukraine with the start of a full-scale invasion of rf in 2022.

“In 2022, Revul bandage appeared again among the wide range of hemostatic agents. As of now, it is a high-quality and effective hemostatic, which is not inferior to alternative products.

The advantages: the convenience of tamponing due to the soft texture of the material, the rate of blood clotting commensurate with its counterparts. In the wound, after removing the bandage, the remains of chitosan fibers are dissolved by enzymes within 24 hours, unlike insoluble kaolin. Revul is a high-quality, highly effective hemostatic bandage.”

Olga Lashko
Volunteer, head of charity fund “Oberig Rodu” (“Talisman for generation”)

“We decided to organize provision of Revul, first of all, to 93-rd air mobile brigade, who is located at one of the hottest zones – village Peski near Donetsk.
When supplies to the army are limited, we are forced to spend medicines reasonably, i.e. use medicines with almost expired best before date. This is why, period, during which Revul could be used, is its additional advantage. Of course, it would be good if there were no need to use it…”

Igor Bykov
Head of Charity organization “International Charity Fund “Hospital of Maidan””

“We received the following feedbacks after practical usage of Revul by wounded people at military zone – ATO: “Revul is easy and applicable to any wound, efficiently stops the bleeding. Excessive amount of medicine is removed from the wound easily by cleaning with 0,9% solution of sodium chloride. Affordability is very important and allows to provide Revul to more staff.”

Sergey Shtrigol
head of pharmacology department at National Pharmaceutical University, Doctor of Medicine, Professor

“Efficacy of Revul is demonstrated in our research on bleeding models of different localizations, including heavy arterial bleeding model.
REVUL approved itself as an efficient hemostatic, has shown positive profile of influence on laboratory parameters, which characterize hemostasis system.
In comparison with its analogues, Revul exceeds in terms of safety, because it has no anaphylactogenic properties.”

Video opinion about Revul (powder) by military medical professional

“I would like to tell about an analogue of Celox but manufactured in Ukraine. The guys brought it to us for the soldiers’ first aid kits. We like a new haemostatic as it is manufactured in Ukraine and is much cheaper than its analogues. I wish every soldier had it in his first aid kit. And it makes me even more proud that this product is manufactured in Ukraine!

It is much-needed as I give medical briefings myself and imported products are very expensive, so we use old tourniquets, and we have very limited quantities of Celox, even though we are at war for over a year now. It would be really good if each soldier had Revul, so please provide our men with it.”

Video opinion about Revul (powder) by the leader of the section for collection and evacuation of the wounded

“One of the main elements of our first aid kits, which we assemble for soldiers who stand at checkpoints and forefront positions, are haemostatic products. In particular, we were given a few samples of haemostatic Revul for testing.

We tried it first on small wounds and then on the larger ones. Basically, Revul has proven itself to be quite effective, so there is an urgent need to replace Celox and Celox-like haemostatics which our soldiers are overloaded with. They cause serious burns of both the eyes and periwound area further on. They should be replaced with a safer haemostatic called Revul.”

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